- - noninvasive
- - Imaging on-the-fly
- - multifocal and manifold examination, over-time examination
- - high spatial resolution and high image contrast
- - portable size, user friendly control, flexible probe, to be compatible with endoscopic gear
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OCT system
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Optical coherence tomography (OCT) is a life-time method for biological tissues structure imaging. The method is referred to as “optical biopsy” owing to high image resolution (20-25 micron) and being an alternative to traditional excisional biopsy when the latter is not possible or undesirable in cases when no cell identification is required. It is best used for investing tissues study. The technique is ideal for studies of investing tissues. The method is registered to be used in Russia (For life-time examination of skin morphology in health and disease by the optical coherence tomography method: Novel medical technology, 2008).
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Central wave length
1300nm
A-Scan Line Rate
92kHz
Scanning depth
1.5mm
Longitudinal resolution
20µm
Lateral resolution
25µm
Sensitivity
90dB
Optical power at object
0.75mW, in compliance with ANSI standard
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ADVANTAGES:
Technical features:
- Visualization occurs as a result of registration of probing emission (low intensity light, near infrared band, up to 1.5mW) radiating back from tissue elements, that come to feature different refractive index and re-radiation characteristics.
- An OCT image is a 2D and 3D image of optical irregularities of the tissue at 1.5mm depth, in pseudocolor brown palette. It is aligned with the cross microscopic section. The imaging orientation is in line with a transversal histological section.
- Principal OCT applications: ophthalmology, gynecology, surgery, carcinology, dentistry, angiology, urology, dermatology, and cosmetology.
- Application in dermatology:
- The method allows to acquire data related to morphological condition of healthy and pathologically modified skin in real time. OCT allows for visual differentiation of the epidermis and upper part of the dermis. The technique is a tool to evaluate the condition of the dermo-epidermal junction area, dermis vessels, sebaceous and sudoriparous glands, hair follicle, all the ungual elements. The OCT visualizes major pathologic processes in dermis, and can be used for life-time diagnostic of dermatoses, inlcuding basal cell carcinoma, melanoma, differential diagnostic of melanomas and nevi, onychopathy. OCT provides for multifocal and manifold examination which allows to monitor abnormal changes during cosmetic procedures and treatments to determine effect and find early signs of side effects (for instance, preclinical development of atrophia cutis during corticosteroid therapy). OCT images are interpreted via the following concepts: structural properties, layering, height, homogeneity, signal intensity within a layer, contrast of layers and areas with different signal intensity, boundary characteristics of layers and areas.